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Advanced Dermal Hydration & Regenerative Medicine

Skin Boosters, Polynucleotides & Cellular Therapies • Sheffield

At The Avenue Skin Clinic (TASC), we offer a curated selection of advanced, injectable skin-remodeling treatments. Unlike traditional dermal fillers that mechanically add volume, these pioneering formulations work at a cellular level to flood the tissue with hydration, trigger intense collagen synthesis, and accelerate natural tissue repair.

All procedures are expert-led, customized to your unique dermal architecture, and administered by John under strict clinical protocols.

Cellular Bio-Remodelling (Profhilo® & Revs PRO32)

The ultimate 5-point face and body structural hydration lift.

These ultra-pure, high-concentration Hyaluronic Acid (HA) matrices feature a potent 64mg blend of both high and low molecular weight HA. Designed to diffuse seamlessly through the tissue, they bio-remodel sagging skin, restore lost elasticity, and smooth fine lines across the face and body.

  • Target Areas: Full face (via the advanced 5-point BAP technique), neck, décolletage, hands, jowls, cheeks, and targeted body areas (laxity on the abdomen, knees, or arms).

  • The Clinical Protocol: A course of 2 sessions spaced 4 weeks apart is highly recommended. Results progressively optimize over 6 weeks and last up to 12 months.

  • Delivery: Available as a comprehensive 5-point facial lift protocol or via precise 2ml targeted syringe applications.

Targeted Brightening Booster (iLLUMA Hydro)

Intense dermal plumping paired with advanced hyperpigmentation management.

A premium, dual-action skin booster engineered to simultaneously tackle profound dehydration and uneven skin tone. This targeted formulation utilizes a smooth, low-viscosity texture for uniform distribution and flawless cellular absorption.

  • The Formulation: Each 2ml syringe delivers 48mg of pure Sodium Hyaluronate for deep plumping, synergized with 10mg of Tranexamic Acid to actively block melanin synthesis and reduce stubborn redness.

  • Key Benefits: Dramatically improves skin clarity, diminishes sun damage, repairs the skin barrier, and imparts an immediate, illuminated glow.

  • Target Areas: Face, neck, décolletage, and hands.

High-Concentration Polynucleotides (LUXIA Bio-Stimulator 9%)

The gold standard in regenerative DNA cell-therapy for the under-eye and face.

Polynucleotides represent the pinnacle of modern regenerative aesthetics. Utilizing ultra-purified, biocompatible DNA fractions, this restorative injectable signals the skin’s own fibroblasts to repair damaged tissue, flip the cellular switch on collagen production, and rapidly calm underlying inflammation.

  • The Luxury Edge: LUXIA 9% is one of the market's most concentrated formulas (90mg/ml), manufactured in Italy under strict GMP clinical standards to drive profound cellular renewal with minimal downtime.

  • Zero-Volume Rejuvenation: Unlike fillers, polynucleotides restore thickness, elasticity, and pigment balance without altering your natural facial shape.

  • Target Areas: Exceptional for the delicate under-eye hollows, under-brow area, full face, neck, and chest tissue tightening.

  • The Clinical Protocol: A recommended protocol of 3 sessions spaced 3 to 6 weeks apart.

Next-Generation Exosome Therapy (EXOGEN)

Biotech-driven cellular communication featuring 6 billion active exosomes.

EXOGEN redefines non-surgical skin optimization by deploying cutting-edge biotechnology. Delivered via precision micro-injections, this high-performance cocktail uses exosome-rich plant cell media to rapidly coordinate intercellular repair, skin-density recovery, and elite barrier function.

  • The Formulation: An unmatched delivery of 6 billion pure exosomes, synthesized alongside native cytokines, over 250 isolated growth factors, PDRN, and high-concentration Hyaluronic Acid.

  • Key Benefits: Activates rapid epidermal turnover, reverses advanced environmental aging, corrects deep texturing, and promotes profound wound healing.

  • The Clinical Protocol: A premium course of 4 treatments spaced 2 to 3 weeks apart.

Specialized Lip Hydration (LUMI-PRO Lips)

The revolutionary hydration matrix tailored exclusively for delicate lip tissue.

LUMI-PRO Lips is a specialized skin booster designed specifically for the unique structural environment of the lips. This is not a dermal filler—it does not add heavy structural volume or alter the anatomy, making it perfect for standalone smoothing or protecting your existing filler investment.

  • The Formulation: Features 22mg of pure, non-crosslinked Hyaluronic Acid per 1.1ml syringe.

  • Key Benefits: Instantly erases dry, chapped textures, refines vertical lip lines, and creates a soft, plush "plumpness" while maximizing the crisp symmetry of your Cupid's bow.

  • The Clinical Protocol: A course of 2 sessions is recommended for optimum, year-round luminosity.

Exclusive Clinical Combinations & Incentives

  • The TASC Signature Contour & Glow Bundle: Book a Revs PRO32 Skin Booster alongside 3 or 4 areas of anti-wrinkle injections (Botox®/Azzalure®) within the same clinical appointment and save £50.

  • LUMI-PRO Lip Package: Secure your full course of 2 recommended sessions upfront and save 20%.

  • Elite Group Bookings: Coordinate an appointment for a minimum of 4 individuals to receive a 10% concession across your entire Hyaluronic Acid dermal filler treatments. Terms & conditions apply; contact the clinic to coordinate scheduling.

Clinical Consultation Protocol & Booking Policies

To ensure premium safety parameters, patient alignment, and medical compliance, all advanced injectable procedures at The Avenue Skin Clinic strictly adhere to the following mandatory guidelines:

  • Clinical Photography: Standardized "before" photographs of the designated treatment zones are mandatory for your patient file and prescriber review. These images remain strictly confidential and will never be utilized for public marketing or social media without your explicit, signed consent.

  • Booking Financials: A security deposit may be required to secure your consultation slot. We operate a strict 48-hour cancellation and rescheduling policy.

Treatment Name
Single Price
Offer Price
Luxia Polynucleotides 9% - Face & Neck
£300
Luxia Polynucleotides 9% - Under Eye, Face & Neck
£600
Luxia Polynucleotides 9% - Neck
£200
Luxia Polynucleotides 9% - Under Eye
£150
HA Skin Booster 5 Point Face Lift or Neck - Illuma Hydro Booster x1
£125
Luxia Polynucleotides 9% - Face
£200
Luxia Polynucleotides 9% (Course of 3)
20% Off
HA Skin Booster 5 Point Face Lift or Neck - Illuma Hydro Booster x2
£225
Lumi Pro Lip Booster 1ml x2
£250
Lumi Pro Lip Booster 1ml x1
£150

Our Aesthetics Practitioner John Colgrave works Wednesday - Saturday.  Please see our online bookings page to check his availability. 

John Salon
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©2026 by The avenue hair & skin. 

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